Instituto Valenciano de Microbiología

Masía El Romeral
Ctra. de Bétera a San Antonio Km. 0.3
46117 Bétera (Valencia)
Phone. 96 169 17 02
Fax 96 169 16 37
CIF B-96337217


Anaplasma phagocytophilum - Human anaplasmosis (Human granulocytic anaplasmosis, tick-borne fever; Pasture fever) - Molecular diagnosis (PCR).  

Anaplasma phagocytophilum (formerly Ehrlichia phagocytophilum) is a small, intracellular must gram - negative bacteria lacking lipopolysaccharide (United Bacterium; phylum Proteobacteria; Class Alphaproteobacteria; Order Rickettsial; Family Ehrlichiaceae; Gender Anaplasma), with tropism by neutrophils that invade, causing anaplasmosis in sheep and cattle, also known as tick - borne fever and fever pasture. In people cause a zoonotic disease called human granulocytic anaplasmosis.

This disease is transmitted by ticks and infects granulocytic neutrophil myeloid series, initially localized in an endosome, where it divides by binary fission, growing in groups called morulae.

Although this disease is known as pathogenic animals since 1932, the human granulocytic anaplasmosis was first described in 1990 in a febrile patient in Wisconsin (USA), who had been bitten two weeks earlier by a tick. Other symptoms include headaches, absence of rash, leucopenia, thrombocytopenia and moderate hepatic impairment. Since its incidence has increased and has been found in Europe.  

Diagnostic methods

You can use three methods:

Tests in IVAMI  

Recommended sample:


Preservation and shipment of sample:


Cost of the test: