Cosmetics tests performed at the Instituto Valenciano de Microbiología (IVAMI)

  • Evaluation of the antimicrobial protection of a cosmetic product – Assessment of efficacy (Challenge test) of preservatives. UNE-EN ISO 11930.
  • Evaluation of the antimicrobial protection of a cosmetic product - Assessment of efficacy (Challenge test) of preservatives. European Pharmacopoeia (European Pharmacopoeia).
  • HET CAM (Hen´s Egg Test Coriallantoic membrane). Mucosal irritation in chick embryo chorioallantoic membrane model. ICCVAM (NIH No. 10-7553: 2010) - (see information in the Toxicology area).
  • In vitro Skin sensitization test with TPH-1 cells and detection of induction of CD86 and CD54 markers by flow cytometry (h-CLAT test). OECD Standard 442E - (see information in the Toxicology area).
  • Phototoxicity test (In vitro 3T3 NRU phototoxicity test). OECD 432 Standard - (see information in the Toxicology area).
  • In vitro cytotoxicity test. ISO 10993-5 - (see information in the Toxicology area).
  • Genotoxicity test (Bacterial mutation reversion test). ISO 10993-3, part 3 and OECD 471 - (see information in the Toxicology area).
  • Genotoxicity test (In vitro mutation test with mammalian cell genes, ISO 10993-3, part 3 and OECD 476 - (see information in the Toxicology area).
  • Detection and counting of aerobic bacteria. ISO 21149
  • Detection of Escherichia coli. ISO 21150.
  • Detection of Pseudomonas aeruginosa. ISO 22717
  • Detection of Staphylococcus aureus. ISO 22718
  • Detection of Candida albicans. ISO 18416
  • Mold and yeast count. ISO 16212
  • Detection of other microorganisms. ISO 18415
  • Anaerobic bacteria count. FDA-Manual method of analytical bacteriology (BAM).
  • Detection of Burkholderia cepacia. Internal SOP; ISO 18415
  • Detection of Pseudomonas putida. Internal SOP; ISO 18415